(19)

(11)

EP 0 754 065 A1

(12)

(43) Date of publication: 22.01.1997 Bulletin 1997/04 (21) Application number: 95914983.0 (22) Date of filing: 31.03.1995

(51) International Patent Classification (IPC):  A61L 27/ 00( . ) A61L 27/ 38( . ) A61L 27/ 24( . ) A61F 2/ 00( . ) (86) International application number: PCT/US1995/003991 (87) International publication number: WO 1995/026761 (12.10.1995 Gazette 1995/43)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 04.04.1994 US 19940222160 (71) Applicant: COLLAGEN CORPORATION Palo Alto, California 94303-3334 (US)	(72) Inventors: ESTRIDGE, Trudy, D. Santa Clara, CA 95054 (US) RAO, Prema, R. Los Gatos, CA 95032 (US) (74) Representative: Goldin, Douglas Michael  J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)