(19)
(11)
EP 0 755 381 A1
(12)
(43)
Date of publication:
29.01.1997
Bulletin 1997/05
(21)
Application number:
95915853.0
(22)
Date of filing:
06.04.1995
(51)
International Patent Classification (IPC):
A61K
31/
44
( . )
A61K
31/
4427
( . )
A61K
31/
505
( . )
A61P
37/
08
( . )
C07D
213/
64
( . )
C07D
213/
75
( . )
C07D
401/
12
( . )
A61K
31/
4418
( . )
A61K
31/
4433
( . )
A61P
29/
00
( . )
A61P
43/
00
( . )
C07D
213/
69
( . )
C07D
213/
84
( . )
C07D
409/
04
( . )
(86)
International application number:
PCT/EP1995/001262
(87)
International publication number:
WO 1995/028386
(
26.10.1995
Gazette 1995/46)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
(30)
Priority:
13.04.1994
US 19940228246
06.03.1995
US 19950395092
(71)
Applicant:
F. HOFFMANN-LA ROCHE AG
4002 Basel (CH)
(72)
Inventors:
COHEN, Noal
Montclair, NJ 07042 (US)
LEE, Ferdinand, Kwo-chen
Teaneck, NJ 07666 (US)
YAGALOFF, Keith, Alan
Hohokus, NJ 07423 (US)
(54)
SUBSTITUTED PYRIDINE LEUKOTRIENE B 4 ANTAGONISTS