PURIFICATION OF OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATES USING ANION EXCHANGE CHROMATOGRAPHY - Patent 0755400

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EP 0 755 400 A1

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(43)	Date of publication:
	29.01.1997 Bulletin 1997/05

(21)	Application number: 95916332.0

(22)	Date of filing: 07.04.1995

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
C07H 21/ 00^{( . )}
C12N 15/ 10^{( . )}

C07H 1/ 06^{( . )}
C07H 21/ 04^{( . )}

(86)	International application number:
	PCT/US1995/004492

(87)	International publication number:
	WO 1995/027718 (19.10.1995 Gazette 1995/45)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

08.04.1994 US 19940225475

(71)	Applicant: HYBRIDON, Inc.
	Worcester, Massachusetts 01605 (US)

(72)	Inventors:
	TANG, Jin-Yan Shrewsbury, MA 01545 (US) GUO, Que Newton, MA 02166 (US) AGRAWAL, Sudhir Shrewsbury, MA 01545 (US)

(74)	Representative: Vossius, Volker, Dr., et al
	Dr. Volker Vossius, Patentanwaltskanzlei - Rechtsanwaltskanzlei, Holbeinstrasse 5 81679 München 81679 München (DE)

(54)	PURIFICATION OF OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATES USING ANION EXCHANGE CHROMATOGRAPHY