INCREASED BIOAVAILABILITY OF BIOLOGICALLY ACTIVE COMPOUNDS BY LINKING TO POLYPYRROLECARBOXAMIDONAPHTHALENE DERIVATIVES - Patent 0758339

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EP 0 758 339 A1

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(43)	Date of publication:
	19.02.1997 Bulletin 1997/08

(21)	Application number: 96904024.0

(22)	Date of filing: 08.02.1996

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International Patent Classification (IPC):

A61K 31/ 40^{( . )}
A61K 31/ 7028^{( . )}
A61K 31/ 704^{( . )}
A61K 47/ 48^{( . )}
C07D 207/ 34^{( . )}
C07D 405/ 14^{( . )}
C07H 15/ 252^{( . )}
C07K 5/ 08^{( . )}
C07K 7/ 02^{( . )}

A61K 31/ 70^{( . )}
A61K 31/ 7034^{( . )}
A61K 38/ 00^{( . )}
A61P 31/ 04^{( . )}
C07D 405/ 12^{( . )}
C07D 491/ 22^{( . )}
C07K 5/ 06^{( . )}
C07K 5/ 10^{( . )}
C07K 7/ 06^{( . )}

(86)	International application number:
	PCT/EP1996/000528

(87)	International publication number:
	WO 1996/026950 (06.09.1996 Gazette 1996/40)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE

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Priority:

01.03.1995 GB 19950004065

(71)	Applicant: Pharmacia S.p.A.
	20152 Milano (IT)

(72)	Inventors:
	MONGELLI, Nicola I-20137 Milan (IT) BIASOLI, Giovanni I-21026 Gavirate (IT) LOMBARDI BORGIA, Andrea I-20067 Paullo (IT) CIOMEI, Marina I-27020 Torre d'Isola (IT) PESENTI, Enrico I-20093 Cologno Monzese (IT) ANGELUCCI, Francesco I-20146 Milan (IT)

(74)	Representative: Ferrario, Vittorino
	Pharmacia & Upjohn S.p.A. Patent and Trademark Department, Viale Pasteur, 10 20014 Nerviano (Milano) 20014 Nerviano (Milano) (IT)

(54)	INCREASED BIOAVAILABILITY OF BIOLOGICALLY ACTIVE COMPOUNDS BY LINKING TO POLYPYRROLECARBOXAMIDONAPHTHALENE DERIVATIVES