MAC-1 I-DOMAIN PROTEIN USEFUL IN BLOCKING ADHESION AND MIGRATION OF NEUTROPHILS - Patent 0758393

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EP 0 758 393 A1

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(43)	Date of publication:
	19.02.1997 Bulletin 1997/08

(21)	Application number: 95917555.0

(22)	Date of filing: 19.04.1995

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61P 29/ 00^{( . )}
C07K 14/ 78^{( . )}
C12N 1/ 21^{( . )}
C12R 1/ 19^{( . )}

A61K 38/ 00^{( . )}
C07K 14/ 705^{( . )}
C07K 19/ 00^{( . )}
C12P 21/ 02^{( . )}

(86)	International application number:
	PCT/US1995/004439

(87)	International publication number:
	WO 1995/029243 (02.11.1995 Gazette 1995/47)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	LT SI

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Priority:

26.04.1994 US 19940233596

(71)	Applicant: PHARMACIA & UPJOHN COMPANY
	Kalamazoo, Michigan 49001 (US)

(72)	Inventors:
	HEINRIKSON, Robert, L. Kalamazoo, MI 49008 (US) ANDERSON, Donald, C. Portage, MI 49009 (US) TOMICH, Che-Shen, C. Kalamazoo, MI 49008 (US) FAIRBANKS, Michael, B. Kalamazoo, MI 49004 (US) BAJT-JAESCHKE, Mary, L. Kalamazoo, MI 49009 (US)

(74)	Representative: Perry, Robert Edward, et al
	GILL JENNINGS & EVERY Broadgate House 7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)

(54)	MAC-1 I-DOMAIN PROTEIN USEFUL IN BLOCKING ADHESION AND MIGRATION OF NEUTROPHILS