(19)

(11)

EP 0 758 402 A1

(12)

(43) Date of publication: 19.02.1997 Bulletin 1997/08 (21) Application number: 95916782.0 (22) Date of filing: 27.04.1995

(51) International Patent Classification (IPC):  C12N 15/ 10( . ) C12Q 1/ 68( . ) (86) International application number: PCT/GB1995/000964 (87) International publication number: WO 1995/029258 (02.11.1995 Gazette 1995/47)

(84) Designated Contracting States: DE FR GB IT (30) Priority: 27.04.1994 GB 19940008344 (71) Applicant: ST.JAMES'AND SEACROFT UNIVERSITY HOSPITALS NHS TRUST Leeds LS9 7TF (GB)	(72) Inventor: TAYLOR, Graham, Roy Leeds LS16 7DQ (GB) (74) Representative: Skerrett, John Norton Haigh  H.N. & W.S. SKERRETT Charles House 148/9 Great Charles Street Birmingham B3 3HT Birmingham B3 3HT (GB)