HALOMETHYL AMIDES AS IL-1$g(b) PROTEASE INHIBITORS - Patent 0758891

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(11)

EP 0 758 891 A1

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(43)	Date of publication:
	26.02.1997 Bulletin 1997/09

(21)	Application number: 95918877.0

(22)	Date of filing: 28.04.1995

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International Patent Classification (IPC):

C07D 521/ 00^{( . )}
A61K 31/ 165^{( . )}
A61K 31/ 275^{( . )}
A61P 11/ 00^{( . )}
A61P 29/ 00^{( . )}
C07C 233/ 05^{( . )}
C07C 233/ 47^{( . )}
C07C 255/ 25^{( . )}
C07C 311/ 06^{( . )}

A61K 31/ 16^{( . )}
A61K 31/ 18^{( . )}
A61K 31/ 33^{( . )}
A61P 25/ 00^{( . )}
A61P 43/ 00^{( . )}
C07C 233/ 13^{( . )}
C07C 255/ 24^{( . )}
C07C 311/ 02^{( . )}
C07C 311/ 24^{( . )}

(86)	International application number:
	PCT/US1995/005347

(87)	International publication number:
	WO 1995/029672 (09.11.1995 Gazette 1995/48)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

29.04.1994 US 19940236425

(71)	Applicant: SANOFI WINTHROP, INC.
	New York, NY 10016 (US)

(72)	Inventors:
	DOLLE, Roland E. King of Prussia, PA 19406 (US) RINKER, James M. Hamden, CT 06518 (US)

(74)	Representative: Le Guen, Gérard, et al
	CABINET LAVOIX 2, place d'Estienne d'Orves 75441 Paris Cédex 09 75441 Paris Cédex 09 (FR)

(54)	HALOMETHYL AMIDES AS IL-1$g(b) PROTEASE INHIBITORS