(19)

(11)

EP 0 758 902 A1

(12)

(43) Date of publication: 26.02.1997 Bulletin 1997/09 (21) Application number: 95918988.0 (22) Date of filing: 04.05.1995

(51) International Patent Classification (IPC):  A61K 38/ 00( . ) A61K 39/ 00( . ) A61P 43/ 00( . ) A61K 38/ 21( . ) A61P 25/ 00( . ) C07K 14/ 47( . ) (86) International application number: PCT/US1995/005605 (87) International publication number: WO 1995/030435 (16.11.1995 Gazette 1995/49)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: LT LV SI (30) Priority: 10.05.1994 US 19940241246 25.10.1994 US 19940328224 (71) Applicant: IMMULOGIC PHARMACEUTICAL CORPORATION Waltham, Massachusetts 02154 (US)	(72) Inventors: HSU, Di-Hwei Palo Alto, CA 94304 (US) SMILEK, Dawn Saratoga, CA 95070 (US) SHI, Jia, Dong Mountain View, CA 94041 (US) (74) Representative: Hutchins, Michael Richard, et al  FRY HEATH & SPENCE The Old College 53 High Street Horley Surrey RH6 7BN Horley Surrey RH6 7BN (GB)