(19)

(11)

EP 0 759 750 A1

(12)

(43) Date of publication: 05.03.1997 Bulletin 1997/10 (21) Application number: 95921256.0 (22) Date of filing: 11.05.1995

(51) International Patent Classification (IPC):  A61K 45/ 06( . ) (86) International application number: PCT/US1995/006044 (87) International publication number: WO 1995/031194 (23.11.1995 Gazette 1995/50)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 11.05.1994 US 19940241603 (71) Applicant: SHAPIRO, Howard, K. Narberth, PA 19072 (US)	(72) Inventor: SHAPIRO, Howard, K. Narberth, PA 19072 (US) (74) Representative: Weinhold, Peter, Dr.  Patentanwälte Dr. Weinhold, Dannenberg, Dr. Gudel, Schubert Siegfriedstrasse 8 80803 München 80803 München (DE)