MODULATOR OF TNF/NGF SUPERFAMILY RECEPTORS AND SOLUBLE OLIGOMERIC TNF/NGF SUPERFAMILY RECEPTORS

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EP 0 759 984 A1

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(43)	Date of publication:
	05.03.1997 Bulletin 1997/10

(21)	Application number: 95919787.0

(22)	Date of filing: 11.05.1995

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International Patent Classification (IPC):

G01N 33/ 566^{( . )}
A61K 35/ 76^{( . )}
A61K 48/ 00^{( . )}
C07H 21/ 04^{( . )}
C07K 14/ 48^{( . )}
C07K 14/ 715^{( . )}
C12N 1/ 21^{( . )}
C12N 15/ 09^{( . )}
C12P 21/ 02^{( . )}
C12R 1/ 19^{( . )}
C12R 1/ 91^{( . )}

A61K 31/ 70^{( . )}
A61K 38/ 00^{( . )}
A61P 35/ 00^{( . )}
C07K 14/ 47^{( . )}
C07K 14/ 525^{( . )}
C12N 1/ 19^{( . )}
C12N 5/ 10^{( . )}
C12N 15/ 12^{( . )}
C12Q 1/ 68^{( . )}
C12R 1/ 645^{( . )}

(86)	International application number:
	PCT/US1995/005854

(87)	International publication number:
	WO 1995/031544 (23.11.1995 Gazette 1995/50)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	LT LV SI

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Priority:

11.05.1994 IL 19940109632
02.10.1994 IL 19940111125

(71)	Applicant: YEDA RESEARCH & DEVELOPMENT COMPANY, LTD.
	76100 Rehovot (IL)

(72)	Inventors:
	WALLACH, David 76406 Rehovot (IL) BOLDIN, Mark Moscow, 103575 (RU) METT, Igor 76462 Rehovot (IL) VARFOLOMEEV, Eugene, Dept. of Membrane Research 76100 Rehovot (IL)

(74)	Representative: VOSSIUS & PARTNER
	Postfach 86 07 67 81634 München 81634 München (DE)

(54)	MODULATOR OF TNF/NGF SUPERFAMILY RECEPTORS AND SOLUBLE OLIGOMERIC TNF/NGF SUPERFAMILY RECEPTORS