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(11)

EP 0 760 012 A1

(12)

(43) Date of publication: 05.03.1997 Bulletin 1997/10 (21) Application number: 94920140.0 (22) Date of filing: 10.06.1994

(51) International Patent Classification (IPC):  C12N 15/ 10( . ) G01N 33/ 50( . ) C40B 40/ 02( . ) (86) International application number: PCT/US1994/006543 (87) International publication number: WO 1995/034683 (21.12.1995 Gazette 1996/02)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: SYMBIOTECH, INC. Woburn, MA 01801 (US)	(72) Inventors: RAY, Bryan L. Burlington, MA 01803 (US) LIN, Edmund C.C. Boston, MA 02108 (US) CREA, Roberto Belmont, MA 02178 (US) (74) Representative: Vossius, Volker, Dr., et al  Dr. Volker Vossius, Patentanwaltskanzlei - Rechtsanwaltskanzlei, Holbeinstrasse 5 81679 München 81679 München (DE)