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(11)

EP 0 760 680 A1

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(43) Date of publication: 12.03.1997 Bulletin 1997/11 (21) Application number: 95919524.0 (22) Date of filing: 22.05.1995

(51) International Patent Classification (IPC):  A61K 47/ 40( . ) A61K 31/ 192( . ) A61K 31/ 5415( . ) A61K 47/ 48( . ) A61K 9/ 00( . ) A61K 31/ 196( . ) A61K 31/ 545( . ) (86) International application number: PCT/GB1995/001152 (87) International publication number: WO 1995/032737 (07.12.1995 Gazette 1995/52)

(84) Designated Contracting States: AT BE DE ES FR GB IT (30) Priority: 27.05.1994 ZA 19940003740 (71) Applicant: FARMARC NEDERLAND BV 1007 JE Amsterdam (NL)

(72) Inventors: PENKLER, Lawrence John Port Elizabeth 6070 (ZA) GLINTENKAMP, Luéta-Ann Port Elizabeth 6055 (ZA) BODLEY, Mark David Port Elizabeth 6070 (ZA) VAN OUDTSHOORN, Michiel Coenraad Bosch Monument Park Pretoria 0181 (ZA) STUBBS, Christopher Port Elizabeth 6001 (ZA) (74) Representative: Wain, Christopher Paul  A.A. THORNTON & CO. Northumberland House 303-306 High Holborn London WC1V 7LE London WC1V 7LE (GB)