(19)
(11) EP 0 760 810 A1

(12)

(43) Date of publication:
12.03.1997 Bulletin 1997/11

(21) Application number: 95920644.0

(22) Date of filing: 24.05.1995
(51) International Patent Classification (IPC): 
C07C 255/ 31( . )
C07C 255/ 45( . )
C07C 253/ 30( . )
C07C 403/ 20( . )
(86) International application number:
PCT/US1995/006580
(87) International publication number:
WO 1995/032946 (07.12.1995 Gazette 1995/52)
(84) Designated Contracting States:
DE ES FR GB IT

(30) Priority: 27.05.1994 US 19940250275

(71) Applicant: LIGAND PHARMACEUTICALS, INC.
San Diego, CA 92121 (US)

(72) Inventor:
  • BENNANI, Youssef, L.
    San Diego, CA 92121 (US)

(74) Representative: Fürniss, Peter, Dr. 
Kuhnen, Wacker & Partner Alois-Steinecker-Strasse 22
85354 Freising
85354 Freising (DE)

   


(54) METHODS FOR THE SYNTHESIS OF 9-CIS RETINOIDS AND THEIR NOVEL INTERMEDIATES