(19)
(11) EP 0 764 203 A1

(12)

(43) Date of publication:
26.03.1997 Bulletin 1997/13

(21) Application number: 95904778.0

(22) Date of filing: 01.12.1994
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
A61K 48/ 00( . )
C07K 7/ 06( . )
C07K 14/ 705( . )
C07K 16/ 28( . )
C12N 5/ 10( . )
C12P 21/ 08( . )
 A61K 35/ 14( . )
A61P 37/ 04( . )
C07K 7/ 08( . )
C07K 14/ 725( . )
C12N 5/ 0783( . )
C12N 15/ 09( . )
(86) International application number:
PCT/US1994/013782
(87) International publication number:
WO 1995/033823 (14.12.1995 Gazette 1996/01)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 03.06.1994 US 19940253751
03.06.1994 US 19940253964

(71) Applicants:
  • THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY
    Arlington, VA 22217-5660 (US)
  • THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN
    Ann Arbor, Michigan 48109-1280 (US)
  • REPLIGEN CORPORATION
    Cambridge, MA 02139 (US)
  • DANA FARBER CANCER INSTITUTE
    Boston Massachusetts 02115 (US)

(72) Inventors:
  • JUNE, Carl, H.
    Rockville, MD 20850 (US)
  • THOMPSON, Craig, B.
    Chicago, IL 60637 (US)
  • NABEL, Gary, J.
    Ann Arbor, MI 48105 (US)
  • GRAY, Gary, S.
    Brookline, MA 02146 (US)
  • RENNERT, Paul, D.
    Holliston, MA 01746 (US)
  • FREEMAN, Gordon, J.
    Brookline, MA 02146 (US)

(74) Representative: VOSSIUS & PARTNER 
Postfach 86 07 67
81634 München
81634 München (DE)

   


(54) METHODS FOR SELECTIVELY STIMULATING PROLIFERATION OF T CELLS