(19)

(11)

EP 0 765 341 A1

(12)

(43) Date of publication: 02.04.1997 Bulletin 1997/14 (21) Application number: 95923900.0 (22) Date of filing: 16.06.1995

(51) International Patent Classification (IPC):  C07D 207/ 16( . ) C07K 7/ 64( . ) C07K 1/ 04( . ) C07K 17/ 08( . ) (86) International application number: PCT/US1995/007620 (87) International publication number: WO 1995/034577 (21.12.1995 Gazette 1996/02)

(84) Designated Contracting States: BE CH DE FR GB IT LI NL (30) Priority: 16.06.1994 US 19940260933 (71) Applicant: SMITHKLINE BEECHAM CORPORATION King of Prussia, PA 19406-0939 (US)	(72) Inventors: MOORE, Michael, Lee Media, PA 19063 (US) NEWLANDER, Kenneth, Allen West Chester, PA 19382 (US) (74) Representative: Lawton, Peter Philip, et al  SmithKline Beecham plc, Corporate Intellectual Property, Two New Horizons Court Brentford, Middlesex TW8 9EP Brentford, Middlesex TW8 9EP (GB)