(19)
(11) EP 0 766 579 A1

(12)

(43) Date of publication:
09.04.1997 Bulletin 1997/15

(21) Application number: 95925294.0

(22) Date of filing: 23.06.1995
(51) International Patent Classification (IPC): 
A61N 1/ 30( . )
A61N 1/ 32( . )
(86) International application number:
PCT/US1995/007951
(87) International publication number:
WO 1996/000111 (04.01.1996 Gazette 1996/02)
(84) Designated Contracting States:
AT BE DE FR GB IE IT

(30) Priority: 24.06.1994 US 19940265306

(71) Applicant: CYGNUS, INC.
Redwood City, CA 94063 (US)

(72) Inventors:
  • WONG, Ooi
    Fremont, CA 94536 (US)
  • CHEN, Tung-Fen
    Sunnyvale, CA 94087 (US)
  • POTTS, Russell O.
    San Francisco, CA 94114 (US)
  • BOMMANNAN, Durairaj Bommi
    Mountain View, CA 94043 (US)

(74) Representative: Goldin, Douglas Michael, et al 
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) PULSATILE DELIVERY SYSTEMS OF BIOLOGICALLY ACTIVE AGENTS USING ELECTRO VOLTAGE PULSING FOR CONTROLLING MEMBRANE PERMEABILITY