(19)
(11) EP 0 767 792 A1

(12)

(43) Date of publication:
16.04.1997 Bulletin 1997/16

(21) Application number: 95926152.0

(22) Date of filing: 29.06.1995
(51) International Patent Classification (IPC): 
A61K 31/ 415( . )
A61K 31/ 44( . )
A61K 31/ 443( . )
A61K 31/ 454( . )
A61K 31/ 495( . )
A61K 31/ 55( . )
A61P 9/ 10( . )
A61P 29/ 00( . )
A61P 43/ 00( . )
C07D 233/ 56( . )
C07D 235/ 14( . )
C07D 243/ 14( . )
C07D 401/ 12( . )
C07D 403/ 06( . )
C07D 403/ 14( . )
C07D 405/ 14( . )
C07D 417/ 12( . )
C07D 491/ 04( . )
 A61K 31/ 4184( . )
A61K 31/ 4427( . )
A61K 31/ 445( . )
A61K 31/ 47( . )
A61K 31/ 496( . )
A61K 31/ 551( . )
A61P 19/ 10( . )
A61P 35/ 00( . )
C07D 223/ 16( . )
C07D 233/ 64( . )
C07D 235/ 20( . )
C07D 401/ 06( . )
C07D 401/ 14( . )
C07D 403/ 12( . )
C07D 405/ 12( . )
C07D 413/ 12( . )
C07D 471/ 04( . )
C07D 491/ 056( . )
(86) International application number:
PCT/US1995/008306
(87) International publication number:
WO 1996/000730 (11.01.1996 Gazette 1996/03)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
SI

(30) Priority: 29.06.1994 US 19940267695
25.04.1995 US 19950428933

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
King of Prussia, PA 19406-0939 (US)

(72) Inventors:
  • ALI, Fadia
    Cherry Hill, NJ 08003 (US)
  • BONDINELL, William
    Wayne, PA 19087 (US)
  • HUFFMAN, William, Francis
    Malvern, PA 19355 (US)
  • LAGO, M., Amparo
    Audubon, PA 19403 (US)
  • KEENAN, Richard, McCulloch
    Malvern, PA 19355 (US)
  • KWON, Chet
    King of Prussia, PA 19406 (US)
  • MILLER, William, Henry
    Schwenksville, PA 19473 (US)
  • NGUYEN, Thomas
    King of Prussia, PA 19446 (US)
  • TAKATA, Dennis, T.
    Flourtown, PA 19031 (US)

(74) Representative: Valentine, Jill Barbara 
SmithKline Beecham plc Corporate Intellectual Property, Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) VITRONECTIN RECEPTOR ANTAGONISTS