(19)

(11)

EP 0 769 055 A1

(12)

(43) Date of publication: 23.04.1997 Bulletin 1997/17 (21) Application number: 95923449.0 (22) Date of filing: 30.06.1995

(51) International Patent Classification (IPC):  C07K 14/ 475( . ) C07K 14/ 54( . ) A61K 38/ 00( . ) C07K 14/ 52( . ) C12N 15/ 24( . ) (86) International application number: PCT/GB1995/001528 (87) International publication number: WO 1996/001319 (18.01.1996 Gazette 1996/04)

(84) Designated Contracting States: CH DE DK FR GB IT LI NL (30) Priority: 01.07.1994 GB 19940013316 (71) Applicant: CANCER RESEARCH CAMPAIGN TECHNOLOGY LTD. London NW1 4JL (GB)	(72) Inventors: GREY, Laura, Mary Toronto M5R 2K8 (CA) STAUNTON, David Appleton Oxford OX13 5LF (GB) HUDSON, Keith, Ronald Oxford OX2 6UP (GB) HEATH, John, Kaye Oxford OX2 8AA (GB) (74) Representative: Sexton, Jane Helen, et al  J.A. KEMP & CO. 14 South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)