CONJUGATES OF METAL COMPLEXES AND OLIGONUCLEOTIDES, WHICH SPECIFICALLY BOND TO SPECIFIC TARGET STRUCTURES, AGENTS CONTAINING THESE CONJUGATES, THEIR USE IN NMR DIAGNOSIS AS WELL AS PROCESS FOR THEIR PRODUCTION - Patent 0770146

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EP 0 770 146 A1

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(43)	Date of publication:
	02.05.1997 Bulletin 1997/18

(21)	Application number: 95926850.0

(22)	Date of filing: 12.07.1995

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
C07H 21/ 00^{( . )}

A61K 49/ 08^{( . )}
C12Q 1/ 68^{( . )}

(86)	International application number:
	PCT/EP1995/002686

(87)	International publication number:
	WO 1996/002669 (01.02.1996 Gazette 1996/06)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

14.07.1994 DE 19944424923
05.12.1994 DE 19944445076

(71)	Applicants:
	SCHERING AKTIENGESELLSCHAFT 13353 Berlin (DE) NeXstar Pharmaceuticals, Inc. Boulder, CO 80301 (US)

(72)	Inventors:
	PLATZEK, Johannes D-12621 Berlin (DE) NIEDBALLA, Ulrich D-14195 Berlin (DE) RADÜCHEL, Bernd D-13465 Berlin (DE) MÜHLER, Andreas D - 15366 Neuenhagen (DE) SPECK, Ulrich D-13465 Berlin (DE) BERNDORFF, Dietmar D-13403 Berlin (DE) GOLD, Larry Boulder, CO 80302 (US) PIEKEN, Wolfgang Longmont, CO 80503 (US)

(54)	CONJUGATES OF METAL COMPLEXES AND OLIGONUCLEOTIDES, WHICH SPECIFICALLY BOND TO SPECIFIC TARGET STRUCTURES, AGENTS CONTAINING THESE CONJUGATES, THEIR USE IN NMR DIAGNOSIS AS WELL AS PROCESS FOR THEIR PRODUCTION