(19)
(11) EP 0 771 199 A1

(12)

(43) Date of publication:
07.05.1997 Bulletin 1997/19

(21) Application number: 95928070.0

(22) Date of filing: 14.07.1995
(51) International Patent Classification (IPC): 
C07D 221/ 20( . )
A61K 31/ 415( . )
A61K 31/ 438( . )
A61K 31/ 445( . )
A61K 31/ 4545( . )
A61P 31/ 04( . )
A61P 37/ 00( . )
C07D 401/ 04( . )
C07D 451/ 04( . )
A61K 31/ 4025( . )
A61K 31/ 4178( . )
A61K 31/ 4427( . )
A61K 31/ 454( . )
A61K 31/ 46( . )
A61P 31/ 12( . )
C07D 209/ 54( . )
C07D 403/ 06( . )
C07D 453/ 02( . )
(86) International application number:
PCT/US1995/008866
(87) International publication number:
WO 1996/003123 (08.02.1996 Gazette 1996/07)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL

(30) Priority: 23.07.1994 GB 19940014901

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
King of Prussia, PA 19406-0939 (US)

(72) Inventors:
  • BADGER, Alison Mary
    Bryn Mawr, PA 19101 (US)
  • BUGELSKI, Peter John
    Philadelphia, PA 19118 (US)
  • HERZYK, Danuta J.
    Valley Forge, PA 19481 (US)

(74) Representative: Waters, David Martin, Dr., et al 
Smithkline Beecham plc Corporate Intellectual Property, Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) METHODS