REGULATABLE ELIMINATION OF GENE EXPRESSION, GENE PRODUCT FUNCTION AND ENGINEERED HOST CELLS - Patent 0776335

(19)

(11)

EP 0 776 335 A1

(12)

(43)	Date of publication:
	04.06.1997 Bulletin 1997/23

(21)	Application number: 95930868.0

(22)	Date of filing: 18.08.1995

(51)

International Patent Classification (IPC):

A01K 67/ 027^{( . )}
C07K 7/ 64^{( . )}
C07K 14/ 725^{( . )}
C12N 5/ 10^{( . )}
C12N 15/ 63^{( . )}

A61K 48/ 00^{( . )}
C07K 14/ 715^{( . )}
C07K 19/ 00^{( . )}
C12N 15/ 09^{( . )}
C12P 17/ 18^{( . )}

(86)	International application number:
	PCT/US1995/010591

(87)	International publication number:
	WO 1996/006111 (29.02.1996 Gazette 1996/10)

(84)	Designated Contracting States:
	AT CH DE FR GB LI SE

(30)

Priority:

18.08.1994 US 19940292595
18.08.1994 US 19940292596
18.08.1994 US 19940292597

(71)	Applicant: ARIAD GENE THERAPEUTICS, INC.
	Cambridge, MA 02139 (US)

(72)	Inventors:
	BRUGGE, Joan, S. Concord, MA 01742 (US) CRABTREE, Gerald, R. Woodside, CA 94062 (US)

(74)	Representative: Marchant, James Ian, et al
	Elkington and Fife, Prospect House, 8 Pembroke Road Sevenoaks, Kent TN13 1XR Sevenoaks, Kent TN13 1XR (GB)

(54)	REGULATABLE ELIMINATION OF GENE EXPRESSION, GENE PRODUCT FUNCTION AND ENGINEERED HOST CELLS