(19)

(11)

EP 0 777 682 A1

(12)

(43) Date of publication: 11.06.1997 Bulletin 1997/24 (21) Application number: 95923629.0 (22) Date of filing: 14.06.1995

(51) International Patent Classification (IPC):  A61K 38/ 00( . ) A61P 37/ 06( . ) C07K 5/ 107( . ) A61P 25/ 02( . ) C07K 5/ 02( . ) C07K 5/ 11( . ) (86) International application number: PCT/SE1995/000721 (87) International publication number: WO 1995/035316 (28.12.1995 Gazette 1996/03)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: LT LV SI (30) Priority: 25.08.1994 SE 19940002838 (71) Applicant: Astra Aktiebolag 151 85 Södertälje (SE)	(72) Inventor: SCHILLER, Peter-Appartement 1212 Montréal, Québec H3G 2A4 (CA)