7-AZABICYCLO 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS - Patent 0778835

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(11)

EP 0 778 835 A1

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(43)	Date of publication:
	18.06.1997 Bulletin 1997/25

(21)	Application number: 95932333.0

(22)	Date of filing: 25.08.1995

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International Patent Classification (IPC):

A61K 31/ 40^{( . )}
A61K 31/ 425^{( . )}
A61K 31/ 445^{( . )}
A61K 31/ 495^{( . )}
A61P 25/ 02^{( . )}
A61P 29/ 00^{( . )}
C07D 487/ 18^{( . )}
C07D 495/ 18^{( . )}

A61K 31/ 415^{( . )}
A61K 31/ 44^{( . )}
A61K 31/ 47^{( . )}
A61K 31/ 505^{( . )}
A61P 25/ 04^{( . )}
C07D 487/ 08^{( . )}
C07D 491/ 147^{( . )}
C07F 9/ 6561^{( . )}

(86)	International application number:
	PCT/US1995/010884

(87)	International publication number:
	WO 1996/006093 (29.02.1996 Gazette 1996/10)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

25.08.1994 US A 296463
21.08.1995 US A 2551

(71)	Applicant: UNIVERSITY OF VIRGINIA
	Charlottesville, VA 22906 (US)

(72)	Inventors:
	SHEN, T., Y. Charlottesville, VA 22903 (US) HARMAN, W., Dean Earlysville, VA 22936 (US) HUANG, Dao, Fei Charlottesville, VA 22903 (US) GONZALEZ, Javier Casselberry, FL 32707 (US)

(74)	Representative: Bassett, Richard
	ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate Nottingham NG1 1LE Nottingham NG1 1LE (GB)

(54)	7-AZABICYCLO 2.2.1]-HEPTANE AND -HEPTENE DERIVATIVES AS CHOLINERGIC RECEPTOR LIGANDS