(19)

(11)

EP 0 781 330 A1

(12)

(43) Date of publication: 02.07.1997 Bulletin 1997/27 (21) Application number: 95926600.0 (22) Date of filing: 22.06.1995

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C12N 15/ 10( . ) C12N 7/ 00( . ) C12Q 1/ 68( . ) (86) International application number: PCT/US1995/007968 (87) International publication number: WO 1995/035369 (28.12.1995 Gazette 1996/03)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 22.06.1994 US 19940264038 (71) Applicant: Miller, Jeffrey E. Carlsbad, CA 92009 (US)	(72) Inventor: Miller, Jeffrey E. Carlsbad, CA 92009 (US) (74) Representative: Baldock, Sharon Claire, et al  Boult, Wade & Tennant 27 Furnival Street London EC4A 1PQ London EC4A 1PQ (GB)