MICROBIAL SYNTHESIS OF HIV PROTEASE INHIBITORS - Patent 0785786

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EP 0 785 786 A1

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(43)	Date of publication:
	30.07.1997 Bulletin 1997/31

(21)	Application number: 95937602.0

(22)	Date of filing: 20.10.1995

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International Patent Classification (IPC):

C12P 17/ 16^{( . )}
A61K 31/ 496^{( . )}
A61P 37/ 04^{( . )}
C07D 241/ 24^{( . )}
C07D 413/ 06^{( . )}
C12N 7/ 00^{( . )}

A61K 31/ 495^{( . )}
A61P 31/ 12^{( . )}
C07D 241/ 04^{( . )}
C07D 401/ 06^{( . )}
C12N 1/ 20^{( . )}
C12R 1/ 465^{( . )}

(86)	International application number:
	PCT/US1995/013628

(87)	International publication number:
	WO 1996/012492 (02.05.1996 Gazette 1996/20)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

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Priority:

25.10.1994 US 19940328634

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

(72)	Inventors:
	SHAFIEE, Ali Rahway, NJ 07065 (US) CHEN, Shieh-Shung T. Rahway, NJ 07065 (US) ARISON, Byron H. Rahway, NJ 07065 (US) MILLER, Randall R. Rahway, NJ 07065 (US) GARRITY, George M. Rahway, NJ 07065 (US) HEIMBUCH, Brian Rahway, NJ 07065 (US)

(74)	Representative: Cole, William Gwyn
	European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	MICROBIAL SYNTHESIS OF HIV PROTEASE INHIBITORS