(19)
(11)
EP 0 787 151 A1
(12)
(43)
Date of publication:
06.08.1997
Bulletin 1997/32
(21)
Application number:
95941017.0
(22)
Date of filing:
25.11.1995
(51)
International Patent Classification (IPC):
C12N
15/
02
( . )
A61P
29/
00
( . )
C07K
16/
18
( . )
C12P
21/
08
( . )
A61K
39/
395
( . )
A61P
37/
06
( . )
C07K
16/
28
( . )
A61K
38/
00
( . )
(86)
International application number:
PCT/EP1995/004648
(87)
International publication number:
WO 1996/017874
(
13.06.1996
Gazette 1996/27)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
(30)
Priority:
07.12.1994
US 19940350915
(71)
Applicant:
F. HOFFMANN-LA ROCHE AG
4002 Basel (CH)
(72)
Inventors:
NAGY, Zoltan
Verona, NJ 07044 (US)
VIDOVIC, Damir
Fairfield, NJ 07004 (US)
(74)
Representative:
Braun, Axel, et al
F.Hoffmann-La Roche AG Patent Department (PLP), 124 Grenzacherstrasse
4070 Basel
4070 Basel (CH)
(54)
MONOCLONAL ANTIBODY FRAGMENTS HAVING IMMUNOSUPPRESSANT ACTIVITY