(19)
(11) EP 0 787 187 A1

(12)

(43) Date of publication:
06.08.1997 Bulletin 1997/32

(21) Application number: 95937555.0

(22) Date of filing: 10.10.1995
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
C07K 7/ 06( . )
C07K 14/ 47( . )
C07K 14/ 485( . )
C07K 16/ 28( . )
C12N 15/ 02( . )
C12N 15/ 12( . )
C12P 21/ 08( . )
G01N 33/ 577( . )
 A61K 47/ 48( . )
C07K 7/ 08( . )
C07K 14/ 475( . )
C07K 14/ 71( . )
C07K 19/ 00( . )
C12N 15/ 09( . )
C12N 15/ 87( . )
C12Q 1/ 68( . )
A61K 38/ 00( . )
(86) International application number:
PCT/US1995/013524
(87) International publication number:
WO 1996/012019 (25.04.1996 Gazette 1996/18)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 14.10.1994 US 19940323442

(71) Applicant: Bristol-Myers Squibb Company
New York, N.Y. 10154 (US)

(72) Inventors:
  • PLOWMAN, Gregory, D.
    San Carlos, CA 94070 (US)
  • SHOYAB, Mohammed
    Seattle, WA 98199 (US)
  • SIEGALL, Clay
    Edmonds, WA 98020 (US)
  • CULOUSCOU, Jean-Michel
    F-92500 Rueil-Malmaison (FR)
  • HELLSTROM, Ingegerd
    Seattle, WA 98105 (US)
  • HELLSTROM, Karl, E.
    Seattle, WA 98105 (US)

(74) Representative: Kinzebach, Werner, Dr., et al 
Patent Attorneys, Reitstötter, Kinzebach & Partner, Sternwartstrasse 4
81679 München
81679 München (DE)

   


(54) HER4 HUMAN RECEPTOR TYROSINE KINASE