(19)

(11)

EP 0 788 375 A2

(12)

(43) Date of publication: 13.08.1997 Bulletin 1997/33 (21) Application number: 95944855.0 (22) Date of filing: 09.11.1995

(51) International Patent Classification (IPC):  A61K 47/ 48( . ) C07K 1/ 107( . ) (86) International application number: PCT/IB1995/001175 (87) International publication number: WO 1996/041813 (27.12.1996 Gazette 1997/04)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 09.11.1994 US 19940336850 23.02.1995 US 19950394690 (71) Applicants: Offord, Robin Ewart 1257 Croix-de-Rozon (CH) Gaertner, Hubert, f. 74160 Archamps (FR)	(72) Inventors: Offord, Robin Ewart 1257 Croix-de-Rozon (CH) Gaertner, Hubert, f. 74160 Archamps (FR) (74) Representative: Paget, Hugh Charles Edward, et al  MEWBURN ELLIS York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)