ENHANCED IMMUNE RESPONSE BY INTRODUCTION OF CYTOKINE GENE AND/OR COSTIMULATORY MOLECULE B7 GENE IN A RECOMBINANT VIRUS EXPRESSING SYSTEM - Patent 0789774

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EP 0 789 774 A2

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(43)	Date of publication:
	20.08.1997 Bulletin 1997/34

(21)	Application number: 95938706.0

(22)	Date of filing: 02.10.1995

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International Patent Classification (IPC):

C07K 14/ 54^{( . )}
C07K 14/ 705^{( . )}
C12N 15/ 863^{( . )}

C07K 14/ 55^{( . )}
C12N 15/ 12^{( . )}
A61K 39/ 00^{( . )}

(86)	International application number:
	PCT/US1995/012638

(87)	International publication number:
	WO 1996/011279 (18.04.1996 Gazette 1996/17)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

03.10.1994 US 19940317402
07.06.1995 US 19950474639

(71)	Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
	Rockville, MD 20852 (US)

(72)	Inventors:
	ROSENBERG, Steven, A. Bethesda, MD 20817 (US) RESTIFO, Nicholas P., 1815 18th Street N.W. Washington, DC 20009 (US) MOSS, Bernard Bethesda, MD 20814 (US)

(74)	Representative: VOSSIUS & PARTNER
	Postfach 86 07 67 81634 München 81634 München (DE)

(54)	ENHANCED IMMUNE RESPONSE BY INTRODUCTION OF CYTOKINE GENE AND/OR COSTIMULATORY MOLECULE B7 GENE IN A RECOMBINANT VIRUS EXPRESSING SYSTEM