(19)
(11) EP 0 792 283 A1

(12)

(43) Date of publication:
03.09.1997 Bulletin 1997/36

(21) Application number: 95939958.0

(22) Date of filing: 13.11.1995
(51) International Patent Classification (IPC): 
C07D 239/ 54( . )
A61K 48/ 00( . )
A61P 35/ 00( . )
C07D 473/ 34( . )
A61K 38/ 16( . )
A61P 31/ 12( . )
C07D 473/ 18( . )
C07K 14/ 00( . )
(86) International application number:
PCT/US1995/014821
(87) International publication number:
WO 1996/015143 (23.05.1996 Gazette 1996/23)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 14.11.1994 US 19940340073

(71) Applicant: CHIRON CORPORATION
Emeryville, California 94608 (US)

(72) Inventors:
  • RICHTER, Lutz, S.
    Montara, CA 94037 (US)
  • ZUCKERMANN, Ronald, N.
    Berkeley, CA 94708 (US)
  • HORN, Thomas
    Berkeley, CA 94707 (US)

(74) Representative: Goldin, Douglas Michael, et al 
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH