ENZYME GENE THERAPY CATALYSING PRODRUG EXTRACELLULAR CONVERSION

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EP 0 792 366 A1

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(43)	Date of publication:
	03.09.1997 Bulletin 1997/36

(21)	Application number: 95937956.0

(22)	Date of filing: 20.11.1995

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61K 35/ 76^{( . )}
A61K 38/ 45^{( . )}
A61K 38/ 48^{( . )}
A61K 38/ 51^{( . )}
A61K 38/ 53^{( . )}
A61K 47/ 48^{( . )}
A61P 35/ 00^{( . )}
C12N 9/ 16^{( . )}
C12N 9/ 78^{( . )}
C12N 9/ 86^{( . )}

A61K 9/ 127^{( . )}
A61K 38/ 44^{( . )}
A61K 38/ 46^{( . )}
A61K 38/ 50^{( . )}
A61K 38/ 52^{( . )}
A61K 45/ 00^{( . )}
A61K 48/ 00^{( . )}
C12N 5/ 10^{( . )}
C12N 9/ 48^{( . )}
C12N 9/ 84^{( . )}
C12N 15/ 62^{( . )}

(86)	International application number:
	PCT/GB1995/002716

(87)	International publication number:
	WO 1996/016179 (30.05.1996 Gazette 1996/25)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

18.11.1994 GB 19940023367

(71)	Applicant: THE WELLCOME FOUNDATION LIMITED
	Greenford, Middlesex UB6 0NN (GB)

(72)	Inventors:
	DEV, Inderjit Kumar Durham, NC 27713 (US) MOORE, John Tomlin Chapel Hill, NC 27514 (US) OHMSTEDE, Carol-Ann Apex, NC 27502 (US)

(74)	Representative: Rees, Marion Lindsay, et al
	Glaxo Wellcome plc, Glaxo Wellcome House, Intellectual Property Department, Berkeley Avenue Greenford, Middlesex UB6 0NN Greenford, Middlesex UB6 0NN (GB)

(54)	ENZYME GENE THERAPY CATALYSING PRODRUG EXTRACELLULAR CONVERSION