(19)

(11)

EP 0 793 664 A1

(12)

(43) Date of publication: 10.09.1997 Bulletin 1997/37 (21) Application number: 95937952.0 (22) Date of filing: 20.11.1995

(51) International Patent Classification (IPC):  A61K 31/ 485( . ) C07D 489/ 02( . ) A61P 25/ 04( . ) (86) International application number: PCT/GB1995/002712 (87) International publication number: WO 1996/016063 (30.05.1996 Gazette 1996/25)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 22.11.1994 GB 19940023542 (71) Applicant: BRITISH TECHNOLOGY GROUP LIMITED London SE1 6BU (GB)	(72) Inventors: MARPLES, Brian, Arthur Loughborough, Leicestershire LE11 3SJ (GB) TRAYNOR, John, Richard Loughborough, Leicestershire LE11 2RA (GB) (74) Representative: Dolan, Anthony Patrick  British Technology Group 101 Newington Causeway London SE1 6BU London SE1 6BU (GB)