(19)
(11) EP 0 796 088 A1

(12)

(43) Date of publication:
24.09.1997 Bulletin 1997/39

(21) Application number: 95944345.0

(22) Date of filing: 18.12.1995
(51) International Patent Classification (IPC): 
C12N 5/ 00( . )
C07K 14/ 435( . )
A61K 9/ 127( . )
C07K 14/ 46( . )
(86) International application number:
PCT/US1995/016520
(87) International publication number:
WO 1996/020695 (11.07.1996 Gazette 1996/31)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 05.01.1995 US 19950369193

(71) Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Oakland, California 94612-3550 (US)

(72) Inventors:
  • HAYS, Lisa, M.
    Davis, CA 95616 (US)
  • CROWE, John, H.
    Davis, CA 95616 (US)
  • CROWE, Lois, M.
    Davis, CA 95616 (US)
  • FEENEY, Robert, E.
    Davis, CA 95616 (US)

(74) Representative: Thiel, Christian, Dr. Dipl.-Chem., et al 
Schaeferstrasse 18
44623 Herne
44623 Herne (DE)

   


(54) PREVENTION OF LEAKAGE DURING THERMOTROPIC PHASE TRANSITION IN LIPOSOMES AND BIOLOGICAL CELLS