(19)
(11)
EP 0 796 113 A2
(12)
(43)
Date of publication:
24.09.1997
Bulletin 1997/39
(21)
Application number:
95942444.0
(22)
Date of filing:
17.11.1995
(51)
International Patent Classification (IPC):
A61K
47/
48
( . )
A61K
38/
21
( . )
A61K
51/
00
( . )
A61P
35/
02
( . )
C07K
14/
535
( . )
A61K
38/
00
( . )
A61K
38/
22
( . )
A61K
51/
08
( . )
C07K
1/
13
( . )
C07K
14/
55
( . )
(86)
International application number:
PCT/US1995/015072
(87)
International publication number:
WO 1996/015816
(
30.05.1996
Gazette 1996/25)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
LT LV SI
(30)
Priority:
17.11.1994
US 19940342481
(71)
Applicant:
AMGEN INC.
Thousand Oaks, CA 91320-1789 (US)
(72)
Inventors:
LITZINGER, David C.
Thousand Oaks, CA 91360 (US)
RALPH, Lloyd D.
Thousand Oaks, CA 91362 (US)
(74)
Representative:
Brown, John David, et al
FORRESTER & BOEHMERT Franz-Joseph-Strasse 38
80801 München
80801 München (DE)
(54)
STABLE N-TERMINALLY LINKED DTPA:PROTEIN COMPOSITIONS AND METHODS