(19)
(11)
EP 0 799 243 A1
(12)
(43)
Date of publication:
08.10.1997
Bulletin 1997/41
(21)
Application number:
95941474.0
(22)
Date of filing:
27.11.1995
(51)
International Patent Classification (IPC):
C07K
14/
47
( . )
A61K
48/
00
( . )
A61K
38/
00
( . )
(86)
International application number:
PCT/US1995/015353
(87)
International publication number:
WO 1996/016989
(
06.06.1996
Gazette 1996/26)
(84)
Designated Contracting States:
DE FR GB
(30)
Priority:
28.11.1994
US 19940347792
28.04.1995
US 19950431357
01.06.1995
US 19950456623
(71)
Applicant:
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
Philadelpia, PA 19104-4268 (US)
(72)
Inventor:
HALAZONETIS, Thanos D.
Philadelphia, PA 19103 (US)
(74)
Representative:
Hale, Stephen Geoffrey
JY & GW Johnson, Kingsbourne House, 229-231 High Holborn
London WC1V 7DP
London WC1V 7DP (GB)
(54)
p53 PROTEINS WITH ALTERED TETRAMERIZATION DOMAINS