TRANSGENIC ANIMAL LACKING NATIVE AMYLOID PRECURSOR PROTEIN - Patent 0799305

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EP 0 799 305 A1

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(43)	Date of publication:
	08.10.1997 Bulletin 1997/41

(21)	Application number: 95942534.0

(22)	Date of filing: 01.12.1995

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
C07K 14/ 47^{( . )}
C12N 15/ 85^{( . )}

A01K 67/ 027^{( . )}
C12N 5/ 10^{( . )}

(86)	International application number:
	PCT/US1995/015672

(87)	International publication number:
	WO 1996/017926 (13.06.1996 Gazette 1996/27)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

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Priority:

05.12.1994 US 19940349334

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

(72)	Inventors:
	ZHENG, Hui Rahway, NJ 07065 (US) CHEN, Howard Y. Rahway, NJ 07065 (US) TRUMBAUER, Myrna E. Rahway, NJ 07065 (US) VAN DER PLOEG, Leonardus H.T. Rahway, NJ 07065 (US)

(74)	Representative: Thompson, John Dr.
	Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	TRANSGENIC ANIMAL LACKING NATIVE AMYLOID PRECURSOR PROTEIN