LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS

(19)

(11)

EP 0 802 916 A1

(12)

(43)	Date of publication:
	29.10.1997 Bulletin 1997/44

(21)	Application number: 95940923.0

(22)	Date of filing: 21.12.1995

(51)

International Patent Classification (IPC):

A61K^{( . )}
C07K^{( . )}
A61K 31/ 445^{( . )}
A61K 31/ 495^{( . )}
A61P 7/ 02^{( . )}
A61P 9/ 08^{( . )}
A61P 11/ 00^{( . )}
C07D 513/ 04^{( . )}
C07K 5/ 065^{( . )}
C07K 5/ 087^{( . )}
A61K 38/ 00^{( . )}

C07D^{( . )}
A61K 31/ 435^{( . )}
A61K 31/ 47^{( . )}
A61K 31/ 54^{( . )}
A61P 9/ 00^{( . )}
A61P 9/ 10^{( . )}
C07D 487/ 04^{( . )}
C07K 5/ 02^{( . )}
C07K 5/ 078^{( . )}
C07K 5/ 097^{( . )}

(86)	International application number:
	PCT/CA1995/000708

(87)	International publication number:
	WO 1996/019483 (27.06.1996 Gazette 1996/29)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	LT LV SI

(30)

Priority:

22.12.1994 GB 19940026038
17.02.1995 GB 19950003136
22.05.1995 GB 19950010265
22.05.1995 GB 19950010267
22.05.1995 GB 19950010266

(71)	Applicant: BIOCHEM PHARMA INC.
	Laval, Quebec H7V 4A7 (CA)

(72)

Inventors:

(74)	Representative: Jones, Helen Marjorie Meredith, et al
	Gill Jennings & Every, Broadgate House, 7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)

(54)	LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS