(19) |
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(11) |
EP 0 803 243 A3 |
(12) |
EUROPEAN PATENT APPLICATION |
(88) |
Date of publication A3: |
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12.11.1997 Bulletin 1997/46 |
(43) |
Date of publication A2: |
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29.10.1997 Bulletin 1997/44 |
(22) |
Date of filing: 15.04.1997 |
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(51) |
International Patent Classification (IPC)6: A61K 7/16 |
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(84) |
Designated Contracting States: |
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BE DE FR GB IE IT SE |
(30) |
Priority: |
24.04.1996 US 16135
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(71) |
Applicant: PFIZER INC. |
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New York, N.Y. 10017 (US) |
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(72) |
Inventors: |
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- Nelson, Dennis George Anthony
Mountain Lakes,
New Jersey 07046 (US)
- Sheehan, Craig Joseph
Edison,
New Jersey 08817 (US)
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(74) |
Representative: Ruddock, Keith Stephen et al |
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Pfizer Limited,
European Patent Department,
Ramsgate Road Sandwich,
Kent CT13 9NJ Sandwich,
Kent CT13 9NJ (GB) |
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(54) |
Cyclodextrins and phenolic compounds in dental products |
(57) Oral rinse and dentifrice compositions, comprising a phenolic selected from the group
consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures
thereof; and a cyclodextrin selected from the group consisting of hydroxypropyl β-cyclodextrin,
hydroxyethyl β-cyclodextrin, hydroxypropyl γ-cyclodextrin, hydroxyethyl γ-cyclodextrin,
α-cyclodextrin, methyl β-cyclodextrin, and mixtures thereof. These compositions are
useful in retarding the development of plaque, treating gingivitis, and in treating
the presence of micro-organisms in the oral cavity.