(19)
(11) EP 0 804 076 A1

(12)

(43) Date of publication:
05.11.1997 Bulletin 1997/45

(21) Application number: 95938753.0

(22) Date of filing: 19.10.1995
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 31/ 675( . )
A61K 38/ 00( . )
A61K 45/ 00( . )
A61P 31/ 12( . )
C12N 15/ 00( . )
C12R 1/ 92( . )
A61K 31/ 57( . )
A61K 35/ 76( . )
A61K 38/ 13( . )
A61K 48/ 00( . )
A61P 37/ 06( . )
C12N 15/ 861( . )
(86) International application number:
PCT/US1995/013253
(87) International publication number:
WO 1996/012406 (02.05.1996 Gazette 1996/20)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 19.10.1994 US 19940325679
07.06.1995 US 19950478482

(71) Applicant: GENETIC THERAPY, INC.
Gaithersburg, MD 20878 (US)

(72) Inventors:
  • TRAPNELL, Bruce C.
    Kensington, MD 20895 (US)
  • YEI, Soonpin
    Gaithersburg, MD 20878 (US)
  • McCLELLAND, Alan
    Gaithersburg, MD 20882 (US)
  • KALEKO, Michael
    Rockville, MD 20854 (US)
  • SMITH, Theodore
    Germantown, MD 20854 (US)

(74) Representative: LOUIS, PÖHLAU, LOHRENTZ & SEGETH 
Postfach 3055
90014 Nürnberg
90014 Nürnberg (DE)

   


(54) GENE THERAPY INVOLVING CONCURRENT AND REPEATED ADMINISTRATION OF ADENOVIRUSES AND IMMUNOSUPPRESSIVE AGENTS