(19)

(11)

EP 0 804 243 A2

(12)

(43) Date of publication: 05.11.1997 Bulletin 1997/45 (21) Application number: 96902701.0 (22) Date of filing: 17.01.1996

(51) International Patent Classification (IPC):  A61K 9/ 00( . ) A61K 47/ 36( . ) A61K 9/ 20( . ) C08B 30/ 12( . ) (86) International application number: PCT/US1996/000612 (87) International publication number: WO 1996/022110 (25.07.1996 Gazette 1996/34)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 18.01.1995 US 19950375321 (71) Applicant: National Starch and Chemical Investment Holding Corporation Wilmington, Delaware 19809 (US)	(72) Inventors: KASICA, James, J. Whitehouse Station, NJ 08889 (US) THOMAS, David, J. Eagan, MN 55123 (US) ZALLIE, James, P. Hillsborough, NJ 08876 (US) (74) Representative: Hagemann, Heinrich, Dr.rer.nat., Dipl.-Chem., et al  Patentanwälte Hagemann, Braun & Held, Postfach 86 03 29 81630 München 81630 München (DE)