(19)
(11) EP 0 804 542 A1

(12)

(43) Date of publication:
05.11.1997 Bulletin 1997/45

(21) Application number: 95937449.0

(22) Date of filing: 04.10.1995
(51) International Patent Classification (IPC): 
G01N 33/ 569( . )
A61K 39/ 09( . )
A61K 39/ 108( . )
A61P 31/ 04( . )
C12Q 1/ 04( . )
C12R 1/ 01( . )
C12R 1/ 42( . )
A61K 39/ 02( . )
A61K 39/ 106( . )
A61P 1/ 00( . )
C12N 1/ 20( . )
C12Q 1/ 18( . )
C12R 1/ 19( . )
C12R 1/ 63( . )
(86) International application number:
PCT/US1995/013196
(87) International publication number:
WO 1996/011258 (18.04.1996 Gazette 1996/17)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
SI

(30) Priority: 05.10.1994 US 19940318409
03.10.1995 US 19950538543
03.10.1995 US 19950538545

(71) Applicant: Antex Biologics, Inc.
Gaithersburg, MD 20879 (US)

(72) Inventors:
  • PACE, John, L.
    Germantown, MD 20874 (US)
  • WALKER, Richard, I.
    Gaithersburg, MD 20878 (US)
  • FREY, Steven, M.
    Germantown, MD 20874 (US)

(74) Representative: Jones, AndrĂ©e Zena, et al 
CRUIKSHANK & FAIRWEATHER 19 Royal Exchange Square
Glasgow, G1 3AE Scotland
Glasgow, G1 3AE Scotland (GB)

   


(54) METHODS FOR PRODUCING ENHANCED ANTIGENIC ENTERIC BACTERIA AND VACCINES COMPRISING SAME