(19)

(11)

EP 0 804 550 A1

(12)

(43) Date of publication: 05.11.1997 Bulletin 1997/45 (21) Application number: 95906781.0 (22) Date of filing: 06.01.1995

(51) International Patent Classification (IPC):  A61K 35/ 14( . ) C12N 5/ 0783( . ) C07K 16/ 00( . ) (86) International application number: PCT/US1995/000193 (87) International publication number: WO 1995/020649 (03.08.1995 Gazette 1995/33)

(84) Designated Contracting States: DE ES FR GB IT (30) Priority: 27.01.1994 US 19940188262 16.03.1994 US 19940214400 06.09.1994 US 19940300982 (71) Applicant: CELLCOR, INC Newton, MA 02159 (US)	(72) Inventors: BABBITT, Bruce P. N. Easton, MA 02356 (US) ZHANG, Zhengyi J. Needham, MA 02192 (US) OSBAND, Michael E. Brookline, MA 02146 (US) GOODMAN, Joseph James Waltham,MA 02154 (US) CAPLAN, Barry Inn Newton, MA 02159 (US) (74) Representative: Dzieglewska, Hanna Eva  Frank B. Dehn & Co., European Patent Attorneys, 179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)