(19)

(11)

EP 0 804 554 A1

(12)

(43) Date of publication: 05.11.1997 Bulletin 1997/45 (21) Application number: 95933075.0 (22) Date of filing: 11.09.1995

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C12N 5/ 078( . ) C12N 5/ 10( . ) C12N 5/ 077( . ) C12N 5/ 0784( . ) (86) International application number: PCT/US1995/011484 (87) International publication number: WO 1996/007733 (14.03.1996 Gazette 1996/12)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: LT LV SI (30) Priority: 09.09.1994 US 19940303983 07.06.1995 US 19950482206 07.06.1995 US 19950479882 (71) Applicant: ZymoGenetics, Inc. Seattle Washington 98102 (US)	(72) Inventors: MOORE, Emma, E. Seattle, WA 98199 (US) MACKAY, Vivian, L. Seattle, WA 98107 (US) (74) Representative: Brown, John David, et al  FORRESTER & BOEHMERT Franz-Joseph-Strasse 38 80801 München 80801 München (DE)