(19)
(11) EP 0 804 573 A1

(12)

(43) Date of publication:
05.11.1997 Bulletin 1997/45

(21) Application number: 95923784.0

(22) Date of filing: 07.06.1995
(51) International Patent Classification (IPC): 
G01N 33/ 15( . )
C12N 15/ 09( . )
C12N 15/ 85( . )
C12Q 1/ 68( . )
C07K 14/ 51( . )
C12N 15/ 12( . )
C12P 21/ 08( . )
(86) International application number:
PCT/US1995/007349
(87) International publication number:
WO 1995/033831 (14.12.1995 Gazette 1996/01)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
LT LV SI

(30) Priority: 07.06.1994 US 19940255250

(71) Applicant: CREATIVE BIOMOLECULES, INC.
Hopkinton, MA 01748 (US)

(72) Inventors:
  • OZKAYNAK, Engin
    Milford, MA 01757 (US)
  • OPPERMANN, Hermann
    Medway, MA 02053 (US)

(74) Representative: Hutchins, Michael Richard, et al 
FRY HEATH & SPENCE The Old College 53 High Street
Horley Surrey RH6 7BN
Horley Surrey RH6 7BN (GB)

   


(54) METHODS AND COMPOSITIONS FOR MODULATING MORPHOGENIC PROTEIN EXPRESSION