(19)
(11)
EP 0 804 573 A1
(12)
(43)
Date of publication:
05.11.1997
Bulletin 1997/45
(21)
Application number:
95923784.0
(22)
Date of filing:
07.06.1995
(51)
International Patent Classification (IPC):
G01N
33/
15
( . )
C12N
15/
09
( . )
C12N
15/
85
( . )
C12Q
1/
68
( . )
C07K
14/
51
( . )
C12N
15/
12
( . )
C12P
21/
08
( . )
(86)
International application number:
PCT/US1995/007349
(87)
International publication number:
WO 1995/033831
(
14.12.1995
Gazette 1996/01)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
LT LV SI
(30)
Priority:
07.06.1994
US 19940255250
(71)
Applicant:
CREATIVE BIOMOLECULES, INC.
Hopkinton, MA 01748 (US)
(72)
Inventors:
OZKAYNAK, Engin
Milford, MA 01757 (US)
OPPERMANN, Hermann
Medway, MA 02053 (US)
(74)
Representative:
Hutchins, Michael Richard, et al
FRY HEATH & SPENCE The Old College 53 High Street
Horley Surrey RH6 7BN
Horley Surrey RH6 7BN (GB)
(54)
METHODS AND COMPOSITIONS FOR MODULATING MORPHOGENIC PROTEIN EXPRESSION