(19)
(11) EP 0 808 171 A2

(12)

(43) Date of publication:
26.11.1997 Bulletin 1997/48

(21) Application number: 96904600.0

(22) Date of filing: 09.02.1996
(51) International Patent Classification (IPC): 
C07D 307/ 94( . )
A61K 31/ 585( . )
A61K 45/ 06( . )
A61P 7/ 10( . )
A61P 9/ 12( . )
A61K 31/ 365( . )
A61K 38/ 55( . )
A61P 7/ 00( . )
A61P 9/ 00( . )
A61P 43/ 00( . )
(86) International application number:
PCT/US1996/001764
(87) International publication number:
WO 1996/024372 (15.08.1996 Gazette 1996/37)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

(30) Priority: 10.02.1995 US 19950386858

(60) Divisional application:
01128866.9 / 1201248

(71) Applicant: G.D. SEARLE & CO.
Chicago IL 60680-5110 (US)

(72) Inventors:
  • MACLAUGHLAN, Todd, E.
    Grayslake, IL 60030 (US)
  • PEREZ, Alfonso, T.
    Lake Forest, IL 60045 (US)

(74) Representative: Beil, Hans Christoph, Dr., et al 
Hansmann & Vogeser, Patent- und Rechtsanwälte, Postfach 80 01 40
65901 Frankfurt
65901 Frankfurt (DE)

   


(54) COMBINATION OF ANGIOTENSIN CONVERTING ENZYME INHIBITOR, SIDE-EFFECT-REDUCED AMOUNT OF ALDOSTERONE ANTAGONIST AND DIURETIC