(19)
(11) EP 0 809 490 A1

(12)

(43) Date of publication:
03.12.1997 Bulletin 1997/49

(21) Application number: 96905494.0

(22) Date of filing: 09.02.1996
(51) International Patent Classification (IPC): 
C07D 207/ 50( . )
A61K 31/ 165( . )
A61K 31/ 195( . )
A61K 31/ 435( . )
A61K 31/ 50( . )
A61K 45/ 00( . )
A61P 37/ 00( . )
C07D 495/ 14( . )
C12P 21/ 00( . )
G01N 33/ 53( . )
C12R 1/ 19( . )
A61K 31/ 12( . )
A61K 31/ 166( . )
A61K 31/ 40( . )
A61K 31/ 437( . )
A61K 38/ 45( . )
A61P 29/ 00( . )
A61P 43/ 00( . )
C07D 495/ 22( . )
G01N 33/ 15( . )
G01N 33/ 543( . )
(86) International application number:
PCT/US1996/001964
(87) International publication number:
WO 1996/024343 (15.08.1996 Gazette 1996/37)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
SI

(30) Priority: 10.02.1995 US 19950386381
07.03.1995 US 19950400220
30.06.1995 US 19950497357

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
King of Prussia, PA 19406-0939 (US)

(72) Inventor:
  • DUNNINGTON, Damien, John
    Lafayette Hill, PA 19444 (US)

(74) Representative: Connell, Anthony Christopher 
SmithKline Beecham plc Corporate Intellectual Property, Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) USE OF LCK SH2 SPECIFIC COMPOUNDS TO TREAT AUTOIMMUNE DISEASES AND ALLOGRAFT REJECTION