USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR THE TREATMENT OF DISEASES MEDIATED BY TNF-ALPHA - Patent 0809491

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EP 0 809 491 A1

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(43)	Date of publication:
	03.12.1997 Bulletin 1997/49

(21)	Application number: 96902330.0

(22)	Date of filing: 13.02.1996

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International Patent Classification (IPC):

A61K 31/ 00^{( . )}
A61K 31/ 216^{( . )}
A61K 31/ 426^{( . )}

A61K 31/ 16^{( . )}
A61K 31/ 381^{( . )}

(86)	International application number:
	PCT/GB1996/000280

(87)	International publication number:
	WO 1996/025156 (22.08.1996 Gazette 1996/38)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

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Priority:

14.02.1995 GB 19950002858

(71)	Applicant: BRITISH BIOTECH PHARMACEUTICALS LIMITED
	Cowley Oxford, OX4 5LY (GB)

(72)	Inventors:
	HODGKIN, Edward, Eliot Princetown, NJ 08543 (US) MILLER, Karen, Margrete Watlington Road Cowley Oxford OX4 5LY (GB) NEEDHAM, Lindsey, Ann Watlington Road Cowley Oxford 0X4 5LY (GB)

(74)	Representative: Walls, Alan James
	British Biotech Pharmaceuticals Ltd., Watlington Road Oxford OX4 5LY Oxford OX4 5LY (GB)

(54)	USE OF MATRIX METALLOPROTEINASE INHIBITORS FOR THE TREATMENT OF DISEASES MEDIATED BY TNF-ALPHA