(19)

(11)

EP 0 809 699 A1

(12)

(43) Date of publication: 03.12.1997 Bulletin 1997/49 (21) Application number: 96907069.0 (22) Date of filing: 16.02.1996

(51) International Patent Classification (IPC):  G01N 33/ 53( . ) A61P 29/ 00( . ) C07K 14/ 52( . ) C12N 5/ 10( . ) C12N 15/ 19( . ) C12Q 1/ 68( . ) A61K 39/ 395( . ) A61P 43/ 00( . ) C07K 16/ 24( . ) C12N 15/ 09( . ) C12P 21/ 02( . ) A61K 38/ 00( . ) (86) International application number: PCT/US1996/002225 (87) International publication number: WO 1996/025497 (22.08.1996 Gazette 1996/38)

(84) Designated Contracting States: BE DE ES FR GB IT NL (30) Priority: 17.02.1995 US 19950390740 (71) Applicant: INCYTE PHARMACEUTICALS, INC. Palo Alto , CA 94304 (US)	(72) Inventors: COLEMAN, Roger Mountain View, CA 94041 (US) BANDMAN, Olga Mountain View, CA 94043 (US) WILDE, Craig, G. Sunnyvale, CA 94087 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)