(19)

(11)

EP 0 812 202 A1

(12)

(43) Date of publication: 17.12.1997 Bulletin 1997/51 (21) Application number: 95903624.0 (22) Date of filing: 05.12.1994

(51) International Patent Classification (IPC):  C07K 14/ 47( . ) C12N 15/ 12( . ) C07K 16/ 18( . ) A61K 38/ 00( . ) (86) International application number: PCT/US1994/013679 (87) International publication number: WO 1995/015175 (08.06.1995 Gazette 1995/24)

(84) Designated Contracting States: CH DE FR GB IT LI (30) Priority: 05.12.1993 IL 19930107880 (71) Applicant: YEDA RESEARCH & DEVELOPMENT COMPANY, LTD. 76100 Rehovot (IL)	(72) Inventor: ZICK, Yahiel 72910 Carmey Yosef (IL) (74) Representative: VOSSIUS & PARTNER  Postfach 86 07 67 81634 München 81634 München (DE)