(19)
(11) EP 0 813 414 A1

(12)

(43) Date of publication:
29.12.1997 Bulletin 1997/52

(21) Application number: 94931923.0

(22) Date of filing: 18.10.1994
(51) International Patent Classification (IPC): 
A61K 31/ 445( . )
A61K 31/ 675( . )
A61K 45/ 06( . )
A61P 3/ 02( . )
A61P 5/ 00( . )
A61P 43/ 00( . )
A61K 31/ 66( . )
A61K 38/ 04( . )
A61P 3/ 00( . )
A61P 3/ 14( . )
A61P 19/ 10( . )
(86) International application number:
PCT/US1994/011912
(87) International publication number:
WO 1995/011029 (27.04.1995 Gazette 1995/18)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
LT SI

(30) Priority: 19.10.1993 US 19930139296
13.06.1994 US 19940259091

(71) Applicant: Merck & Co., Inc.
Rahway New Jersey 07065-0900 (US)

(72) Inventors:
  • GERTZ, Barry, J.
    Summit, NJ 07901 (US)
  • RODAN, Gideon, A.
    Bryn Mawr, PA 19010 (US)
  • SMITH, Roy, G.
    Westfield, NJ 07090 (US)
  • WYVRATT, Matthew, J.
    Mountainside, NJ 07092 (US)
  • PATCHETT, Arthur, A.
    Westfield, NJ 08090 (US)

(74) Representative: Hiscock, Ian James, et al 
European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) COMBINATION OF BISPHOSPHONATES AND GROWTH HORMONE SECRETAGOGUES